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KMID : 1101420200520010028
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Korean Journal of Clinical Laboratory Science
2020 Volume.52 No. 1 p.28 ~ p.35
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Comparison of Characteristics and Dispersion of Fasting Blood Glucose Data by Administrative Districts and Gender Difference Using the 2017 ‘Korean Blood Glucose Reference Standard’
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Kwon Young-Il
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Abstract
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This study aimed to investigate the differences in the upper and lower limits of the 95% distribution of fasting blood glucose (FBG) by age groups. We also analyzed the changes in the mean values and dispersion of the data using the Korean Blood Glucose Reference Standard raw data published by the National Health Insurance Service (NHIS). Furthermore, the trends among 16 administrative districts were analyzed and any gender differences were determined. We also assessed whether the study results correlated with the relative standard uncertainty, as published by the NHIS. On the dispersion analysis using the differences between the upper and lower limits of the 95% distribution of FBG by age group, there were significant differences across gender and administrative districts (P＜0.05).
The gender differences in FBG measurements, as published by the NHIS, were significant across different administrative districts and age groups (P＜0.001). This confirmed the need to recalculate the blood glucose reference standards for men and women. No significant correlation was observed between the relative standard uncertainty, as published by NHIS, and the dispersion and number of measurements analyzed in this study. However, it showed a high correlation with the measured mean value (R2=0.95). Therefore, further research on the reference standard and uncertainty is needed.
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KEYWORD
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Blood glucose, Reference standard, Uncertainty, 95% distribution, NHIS
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